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Development of a closed-tube, calcein-based loop-mediated isothermal amplification assay to detect Salmonella spp. in raw meat samples
Salmonella spp. are among the main pathogenic bacteria that cause outbreaks globally. Foodborne infections jeopardize…
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A bacteriophage cocktail can efficiently reduce five important Salmonella serotypes both on chicken skin and stainless steel
One of the most significant zoonotic infections, salmonella is primarily spread by eating food that…
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Antimicrobial drug resistance in Salmonella: problems and perspectives in food- and water-borne infections
Antimicrobial drug-resistant strains of Salmonella spp. are becoming common in both industrialized and developing nations.…
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Targeting hypoxia-inducible factors: therapeutic opportunities and challenges
Hypoxia-inducible factors (HIFs) are highly conserved transcription factors that are crucial for adaptation of metazoans…
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Early Cancer Detection in Li–Fraumeni Syndrome with Cell-Free DNA
As you may have heard that Liquid biopsy has become an attractive tool for a…
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AMG 509 (Xaluritamig), an Anti-STEAP1 XmAb 2+1 T-cell Redirecting Immune Therapy with Avidity-Dependent Activity against Prostate Cancer
Researchers promises that AMG 509 provides a targeted immunotherapy approach to engage a patient’s T…
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First-in-Human Study of the Reversible BTK Inhibitor Nemtabrutinib in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia and B-Cell Non–Hodgkin Lymphoma
A recent first-in-human phase I study shows the safety and preliminary efficacy of nemtabrutinib in…
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A new type of antibiotic targets a drug-resistant bacterium
It’s always been hard to treat the Infections caused by drug-resistant strains of the bacterium…
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A global phase 3 study of serplulimab plus chemotherapy as first-line treatment for advanced squamous non-small-cell lung cancer (ASTRUM-004)
A recent study shows that First-line serplulimab plus chemotherapy improves PFS and OS and promises…
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Interferon-stimulated neutrophils as a predictor of immunotherapy response
Researchers indentified interferon-stimulated, Ly6Ehi neutrophils as a blood-borne biomarker of anti-PD1 response in mice at…